Łucja Frey, a trailblazing neurologist in early 20th century Poland, is remembered for her groundbreaking description of auriculotemporal nerve dysfunction. However, her life and career were tragically cut short under the shadow of Nazi persecution. Born in 1889 in Lwów (then part of Austria-Hungary, now Lviv, western Ukraine), Frey was among the first women to graduate in medicine from Jan Kazimierz University. She earned her medical diploma in 1923 and, in the same year, published a seminal paper elucidating the pathophysiology of auriculotemporal nerve dysfunction. Frey recognised the phenomenon in a 25-year-old soldier who had sustained a gunshot wound, accurately describing how aberrant nerve regeneration following parotid injury could lead to gustatory sweating and flushing. This condition, now known as Frey's Syndrome, has critical implications for parotid gland surgeries and remains a focal point of interest in otolaryngology and head and neck surgery. Despite significant gender barriers, Frey specialised in neurology and internal medicine, eventually becoming an assistant professor at the Neurological and Psychiatric Clinic in Warsaw. She amassed a total 43 publications across various topics. Her promising career was abruptly halted with the invasion of Poland during World War II. As a Jewish physician, she faced systemic persecution under Nazi rule. Forced into the Lwów Ghetto, she continued to practice medicine under deplorable conditions, treating fellow prisoners and maintaining her scientific rigor despite immense personal suffering. Frey’s life was tragically cut short in 1942 when she was killed during the liquidation of the ghetto. This presentation honours Łucja Frey’s remarkable achievements and extraordinary resilience, reflecting on her enduring legacy in medicine. Her life serves as a powerful reminder of the profound impact of intellectual curiosity and dedication, even in the face of unspeakable adversity.