ePoster
Presentation Description
Institution: Westmead Hospital - NSW, Australia
Aim
Solitary fibrous tumours (SFTs) are rare mesenchymal neoplasms, accounting for 6% of all SFTs in the head and neck region, with their occurrence in the sinonasal cavity being exceptionally rare (<0.1%). We aim to present a unique case of SFT arising in the nasal vestibule, highlight its clinical presentation, diagnostic challenges, and management, and review relevant literature to contextualise this rare entity.
Methodology
We present the case of a 34-year-old male with a three-month history of progressive nasal obstruction and intermittent epistaxis. Examination revealed a unilateral nasal vestibule lesion with clinical similarities to a pyogenic granuloma. Wide local excision was performed, and the tumour was subjected to histopathological examination and immunohistochemistry (IHC).
Results
Histopathology confirmed a spindle-cell neoplasm with features consistent with SFT. IHC demonstrated strong positivity for CD34 and STAT6, confirming the diagnosis. Literature review identified fewer than 50 cases of SFTs in the nasal cavity and sinuses, with no prior reports specifically involving the vestibule. The majority of nasal SFTs present in adults aged 40-70 and follow a benign course, with malignant transformation observed in 10-20%. Furthermore, this case was discussed in a multidisciplinary team meeting raising the possibility of performing a PET scan for surveillance purposes.
Conclusion
This case represents the first documented instance of an SFT in the nasal vestibule, underscoring its rarity. Accurate diagnosis requires histopathology and IHC, given the tumour's nonspecific presentation. Surgical excision remains the treatment of choice, with favourable outcomes in most cases. This report adds to the limited literature on nasal SFTs and highlights the need for long-term follow-up to monitor for recurrence or malignancy.
Speakers
Authors
Authors
Dr Reza Bigdeli - , Dr Niranjan Sritharan -