Background: Paediatric cervical infections, including cervical lymphadenitis and deep neck space infections, are an important and potentially life-threatening entity. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus emerged in late 2019 and was responsible for the coronavirus disease (COVID-19) pandemic. Non-pharmaceutical interventions (NPIs) implemented to reduce COVID-19 have subsequently changed the epidemiology of many infectious conditions. This study aimed to assess the impact of NPIs directed against COVID-19 on the epidemiology of cervical infections in an Australian paediatric population. Methodology: A retrospective cohort study was conducted at the two main paediatric tertiary hospitals in Sydney, Australia. Children (0-16 years old inclusive) who presented between 1st July 2017-30th June 2019 (pre-COVID-19 cohort) and 1st July 2021-30th June 2023 (post-COVID-19 cohort) with a suppurative cervical infection were included in the study. Detailed clinical and demographic data was extracted. Descriptive analyses, including statistical tests of comparison, were performed to compare the pre-COVID-19 and post-COVID-19 cohorts. Results: 329 patients with cervical infections were included: 150 in the pre-COVID-19 cohort, and 179 in the post-COVID-19 cohort. There was a significant increase in the number of retropharyngeal/parapharyngeal infections in the post-COVID-19 cohort. Additionally, infections overall were more severe (particularly those caused by Streptococcus pyogenes), requiring longer hospital stays. Conclusion: The relaxation of NPIs directed against COVID-19 appears to correlate with an increased incidence and severity of suppurative cervical infections in children in Sydney, Australia. This concurs with the changing epidemiology of infectious diseases in paediatric populations following the pandemic, both within Australia and globally.